Irwin Allan Rose (16. juli 1926 - 2. juni 2015 var en amerikansk biokemiker. I 2004 modtog han nobelprisen i kemi sammen med Aaron Ciechanover og Avram Hershko for opdagelsen af -medieret .
Irwin Rose | |
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Personlig information | |
Født | 16. juli 1926 ![]() Brooklyn, New York, USA ![]() |
Død | 2. juni 2015 (88 år) ![]() Deerfield, Massachusetts, USA ![]() |
Uddannelse og virke | |
Uddannelsessted | University of Chicago, New York University, Lewis and Clark High School ![]() |
Medlem af | National Academy of Sciences, American Academy of Arts and Sciences ![]() |
Beskæftigelse | Universitetsunderviser, biokemiker, kemiker, biolog ![]() |
Fagområde | Biologi ![]() |
Arbejdsgiver | University of Chicago, University of California Irvine ![]() |
Nomineringer og priser | |
Udmærkelser | Guggenheim-Stipendium (1971), Nobelprisen i kemi (2004) ![]() |
Information med symbolet ![]() ![]() ![]() |
![]() | Nobelprisen i kemi 2004 |
Referencer
- Wilkinson, Keith; Hershko, Avram (2015). "Irwin Allan Rose (1926–2015) Established role of ubiquitin in the destruction of cellular proteins". Nature. 523 (7562): 532-532. doi:10.1038/523532a. ISSN 0028-0836.
- Rose, Irwin (2005), "Early work on the ubiquitin proteasome system, an interview with Irwin Rose. Interview by CDD", Cell Death Differ., vol. 12, no. 9, s. 1162-6, doi:10.1038/sj.cdd.4401700, PMID 16094392
- "Nobel Prize in Chemistry, 2004. Aaron Ciechanover, Avram Hershko and Irwin Rose", Indian J. Physiol. Pharmacol., vol. 49, no. 1, s. 121, 2005, PMID 15881872
- Latonen, Leena; Laiho, Marikki (2004), "Nobel prize in chemistry goes to three persons with a key role in revealing the ubiquitin-mediated protein degradation pathway", Duodecim; lääketieteellinen aikakauskirja, vol. 120, no. 24, s. 2868-71, PMID 15700582
- Goldberg, Alfred L (2005), "Nobel committee tags ubiquitin for distinction", Neuron (udgivet 3. februar 2005), vol. 45, no. 3, s. 339-44, doi:10.1016/j.neuron.2005.01.019, PMID 15694320
- Neefjes, J; Groothuis, T A M; Dantuma, N P (2004), "The 2004 Nobel Prize in Chemistry for the discovery of ubiquitin-mediated protein degradation", Nederlands tijdschrift voor geneeskunde (udgivet 25. december 2004), vol. 148, no. 52, s. 2579-82, PMID 15646859
- Hershko, A.; Ciechanover, A.; Rose, I.A. (1979), "Resolution of the ATP-dependent proteolytic system from reticulocytes: a component that interacts with ATP", Proc. Natl. Acad. Sci. USA, 76 (7): 3107-3110, doi:10.1073/pnas.76.7.3107, PMC 383772, PMID 290989.
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